Kinetic mechanisms of receptors, channels and transporters and the integration of these components in mathematical models of cellular signaling pathways constitute the current work of the Center.
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Slide 1: A smooth muscle cell sarcolemma contains channels, receptors, and transporters spanning the membrane.
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Slide 2: A model of BK α in absence and presence of β1.
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Slide 3: Optimized positions of the intracellular end of α S0, β1 TM1, and β1 TM2, relative to S1 – S6 in the absence and presence of β1.
